This involves injection with a small needle of tiny amounts of a fat-dissolving enzyme, phosphatidylcholine. It is used in areas of cellulite and persistent fat pockets such as saddle bags, love handles, etc.
The History of Mesotherapy
Mesotherapy is a technique, invented in 1952 by Dr. Michel Pistor, where medication is injected in the mesoderm, the layer of fat and connective tissue under the skin. Over the past 50+ years, in excess of 15,000 physicians worldwide have used Mesotherapy regularly for a variety of purposes, including overall weight loss, spot weight reduction, cellulite reduction, hair loss, scar revision and wrinkle elimination.
In 1987, the French Academy of Medicine recognized Mesotherapy as an inherent part of traditional medicine. The International Society of Mesotherapy encompasses 14 countries throughout Europe and South America.
Mesotherapy is a technique using very small doses of compounded medications that are administered in specific areas, depending on the condition being treated. The medications and plant extracts used are typically obtained from compounding pharmacies in most countries, although Europe mass manufactures many products that are prohibited for import into most other countries.
All medicines used are FDA-approved for their use. In combination, medicines for Mesotherapy are used for off-label purposes. A recent illustration of this distinction is Botox®. Although Botox® was FDA approved for controlling muscle spasms, the medical community embraced it for its cosmetic properties of controlling wrinkles. For many years, plastic surgeons and dermatologists used Botox® for off-label purposes.
What is Mesotherapy?
Mesotherapy is a series of injections formulated from a cocktail of vitamins, minerals, amino acids and homeopathic remedies which are injected into the skin between the dermis and subquetaneous layers of skin known as the mesoderm.
What Medications are Used in a Mesotherapy Cocktail?
Mixtures of medications and ingredients used to inject in Mesotherapy are commonly called “Mesotherapy Cocktails”. The solutions are formulated to block internal signals of fat uptake, trigger fat release, increase circulation, and burn energy. Medications include: local anesthetics, anti-inflammatories, muscle relaxants, corticoids, vasoactive drugs, immunostimulant agents, metabolic regulators, trace elements, hormones, antibiotics, analgesics, sedatives, biologicals, antihomotoxic preparations, homeopathic medicines, natural plant agents, etc. They should be customized for the needs of each patient and really should be formulated and supplied by a Compounding Pharmacy.
What Ingredients are Used in Mesotherapy?
The following lists indicates common ingredients used in many of the therapies. This list is only a sample of the various ingredients used in Mesotherapy:
Procaine Amino Acids
Lidocaine Glycolic Acid
Retinoic Acid Alpha Lipoic Acid
How are the Mesotherapy Drugs Administered?
Drugs are administered into the most superficial skin layers, a few millimeters under the skin surface. Drug bio-distribution in superficial skin layers is slower than in deep layers where diffusion is more rapid and drugs have both general and local effects.
Why are Anesthetics Administered with Mesotherapy Ingredients?
Anesthetics in the treatment area retard the absorption of the injected drugs and allow them to diffuse deeper into the connective tissue, thus arriving at the desired site of treatment in higher concentration, without a dilution of the drug. Without the application of anesthetics, the drugs may be absorbed. It is because of this that mesotherapy injectables are always performed with Procaine or Lidocaine.
What Areas of the Body can be Treated with Mesotherapy?
Love handles, stomach, saddle bags, bra bulge, inner thigh bulge, outer thighs, buttocks, abdomen, knee pads, double chin, eye fat pads, face and neck, arms, back, legs, hands & waist, head – alopecia, wrinkles – face, neck & chest.
Which Patients are Suitable for Mesotherapy?
Generally, most healthy adults 18 to 80 may have mesotherapy for body sculpting and weight loss, cellulite treatment & “mesolift” skin rejuvenation. Exclusion criteria may include: Women who are pregnant, people on blood thinners, insulin dependent diabetics, people with cancer, people with AIDS, people with coronary artery heart disease or heart dysfunction, people with arrhythmias (irregular heart rhythms), people with a history of blood clots or strokes, or people with immune compromise and/or organ transplant recipients. Cancer patients in remission must also be careful.
What are the Side Effects of Mesotherapy?
Possible side effects are generally mild and may include a short period of burning or itching, as well as temporary soreness which can last from a few minutes to as much as two days. Temporary bruising is common, yet most bruises fade within one week and certainly by two weeks they should be completely gone.
General Effects of Mesotherapy: Tenderness, Pain, Swelling, Bruising
Potential Side Effects: Flushing, Allergy, Nausea, Fainting
Potential Local Effects: Hyperpigmentation, Hematoma, Infection